The course offers introduction in the methods for mathematical modelling of the processes in the brain at level of neural cells and their interactions. Its aim is to familiarize mathematicians and engineers with the basic terminology in neurobiology needed to work in this interdisciplinary fields as well as to make neurobiologists acquainted with possibilities for simulation investigations of different brain structures. The course includes the following topics: introduction to neurobiology and neural cell models (from Hodgink-Huxley to spike timing); models of connections between neurons (dendrites and synapses); brain structures and their modelling at neural cell level; NEST library and its implementation for simulation of neural structures via Python.